According to an interview in French magazine Tele Star, former Prison Break star Sarah Wayne Callies, aka Dr. Sara Tancredi, was forced to
quit the show. Here is a rough translation of the interview (if the magazine is credible):

Big surprise on Prison Break. We hear that you're leaving the show in the third season. Yes, but I didn't have the choice. I'm sad, but it's just show business.

You weren't expecting this? No, at the end of season 2 last year. I was sure I'd continue. It's such a great adventure we achieved.

How did you know you were fired? I don't want to speculate too much about this. I was shocked.

Your leaving the show was a big deal. You have to tell us more! I'll just say this. I am sorry to let down the viewers. I have loved the support Sara Tancredi got from them. and though she was a victim of her own destiny, I liked how she made decisions by herself. But the way things ended up couldn't have been foreseen. Again, I was deceived by the decision.

How did your fellow actors react? They told me 'It's too bad. I loved working with you and good luck, we hope we can work together again.'

And Wentworth [Miller]? We were so sad that we wouldn't work together anymore. Wentworth is a gentleman. He's gracious and full of class. And i learned a lot from him. But in a series like "Prison Break," apart from Wentworth, anyone can go. When I took the role of Sara, I thought it'd be for only a year. Afterwards, I was so happy to get a second year.

If they call you back, will you accept? Of course! I don't have another role right now. Right now, I need to find work.

How will Sara make her exit from the series? I don't know. I'm not part of the team anymore and don't have any influence on the storyline.

How is being a mom to baby Keala? It's a rich experience and unpredictable. You can't plan anything. (Keala was born in July 2007.)

What projects do you currently have today? I'll rest another month in Vancouver (Canada). Afterwards, I'll go to California for a little bit. After that, I'd like to do theater in New York. I honed my skills on the stage and I miss it.

source: http://www.justjared.buznet.com/